How chronic stress hastens the progression of colorectal cancer
A new study, revealing how chronic stress disturbs the balance of gut microbiota to hasten the progression of colorectal cancer (CRC), was presented at the United European Gastroenterology (UEG), the...
View ArticleCollaboration between Lilly and the UK life science sector
At the International Investment Summit on Monday 14 October, it was announced that the UK’s life sciences sector will receive a £279 million boost to combat significant health challenges. Lilly, the...
View ArticleComputational pipeline for personalised cancer vaccine design
Researchers at Ludwig Cancer Research have developed a full computational pipeline to design personalised cancer vaccines. Led by Florian Hiber and Michal Bassani-Sternberg, it integrates molecular and...
View ArticleSuppression of neuropeptide F extends longevity in flies
Researchers at Brown University have found how a neuropeptide hormone produced in the gut of flies can control their lifespan. This could have far-reaching implications for new diabetes and obesity...
View ArticleMechanism that controls reactivation of neural stem cells discovered
Led by Duke-NUS Medical School, an international team of neuroscientists have discovered a mechanism that controls the reactivation of neural stem cells. This finding could advance treatment of common...
View ArticleNew toxic component in the evolution of Alzheimer’s disease
A molecular mechanism that influences RNA processing and alters the process of protein synthesis in the brains of Alzheimer’s disease (AD) patients has been discovered by a research team at the...
View ArticleSpecific HERV expression signatures linked to MS and ALS
Scientists at King’s College London and Northwell Health have discovered a link between ancient viral DNA within the human genome and the genetic risk for two significant neurodegenerative diseases:...
View ArticleThe future of cell analysis: a comprehensive guide
Sartorius, the leading international partner of life sciences research and biopharmaceutical manufacturing, has published its second edition High-Throughput Screening (HTS) by Cytometry handbook....
View ArticleUsing microgravity to address limitations of tissue engineering techniques
Tissue engineering and liver transplantation could be revolutionised following a project conducted on the International Space Station (ISS). The self-assembly of human liver tissues in low Earth orbit...
View ArticleGPNMB: a potential therapeutic agent for cardiovascular disease
Researchers at the UCLA have identified the GPNMB protein (glycoprotein non-metastatic melanoma protein B) as an essential regulator in the heart’s healing process following a heart attack. They showed...
View Articlep53’s role in ulcerative colitis and its progression to cancer
The role of the p53 gene in the pathogenesis of ulcerative colitis (UC) has been revealed by researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité – Universitätsmedizin. Their...
View ArticlePreventing F-actin build-up improves drosophila healthspan
Researchers at UCLA have been able to prevent filamentous actin build-up in the brain of drosophila, which maintained cellular recycling and extended the healthy lifespan of the flies by around 30...
View ArticleNew AI model may enable more targeted prostate cancer treatment
Researchers at Mass General Brigham have trained and validated an AI model based on MRI scans of hundreds of prostate cancer tumours. It was able to identify the edges of 85 percent of the most...
View ArticleINPP4B exerts its tumour-promoting effects via lysosomes
Researchers at the University of Toronto, Toronto Metropolitan University and the Princess Margaret Cancer Centre have discovered new insights into the molecular mechanism that drives the...
View ArticleCarbonic anhydrase inhibitors protect against tau protein build-up
Scientists at the UK Dementia Research Institute, University of Cambridge, have identified a drug commonly used to treat glaucoma can protect against tau protein build-up in the brain in genetically...
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